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SPACELINE Current Consciousness Lists are distributed by means of listserv and could be discovered on the NASA Job E ebook web page at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please ship any correspondence to Shawna Byrd, SPACELINE Current Consciousness Senior Editor, SPACELINE@nasaprs.com.
Identify for articles to cite inside the weekly lists: Authors at NASA Amenities and NASA PIs—do you’ll have an article that has these days revealed or will publish inside the upcoming weeks inside a peer-reviewed journal and is inside the scope of home life sciences? In that case, ship it our method! Ship your article to the e-mail deal with talked about above. Articles acquired by Wednesday will appear inside that week’s file—articles acquired after Wednesday will appear the subsequent week.
Papers deriving from NASA help:
1
Lonner TL, Allred AR, Bonarrigo L, Gopinath A, Smith Okay, Kravets V, Groen EL, Oman C, DiZio P, Lawson BD, Clark TK.
Digital actuality as a countermeasure for astronaut motion sickness all through simulated post-flight water landings.
Exp Thoughts Res. 2023 Oct 5.
https://pubmed.ncbi.nlm.nih.gov/37796301
PI: T.Okay. Clark
Remember: From the abstract: “Entry motion sickness (EMS) impacts crewmembers upon return to Earth following extended adaptation to microgravity. Anticholinergic prescribed drugs (e.g., Meclizine) are generally taken earlier to landing; nonetheless, they’ve operationally hostile undesirable uncomfortable side effects (e.g., drowsiness). There is a should develop non-pharmaceutical countermeasures to EMS. We assessed the efficacy of a technological countermeasure providing exterior seen cues following splashdown, the place in every other case solely nauseogenic inside cabin seen references could be discovered. Our countermeasure supplied motion-congruent seen cues of an Earth-fixed scene in digital actuality, which was compared with a administration scenario with a head-fixed fixation degree in digital actuality in a between-subject design with 15 subjects in each group. We examined the countermeasure’s effectiveness at mitigating motion sickness indicators on the end of a ground-based reentry analog: roughly 1 h of 2Gx centrifugation adopted by as a lot as 1 h of wave-like motion.”
Journal Have an effect on Situation: 2.0
Funding: “This work was supported by the Nationwide Aeronautics and Home Administration Human Evaluation Program beneath Grant No. 80NSSC21K0257. Furthermore, this work was supported by a NASA Home Experience Graduate Evaluation Options Award.”
2
Elder CA, Moore J, Janis BR, Shacklette S, Jones C, Cantrell R, Grimm DF, Pantalos G, Kopechek JA, Menze MA.
Rehydration outcomes for freeze-dried pink blood cells in lowered gravity.
Acta Astronaut. 2023 Oct 10. On-line ahead of print.
https://doi.org/10.1016/j.actaastro.2023.10.006
Remember: From the abstract: “This look at explores if freeze-dried RBCs [red blood cells] could also be rehydrated and transfused in lowered gravity with associated outcomes in restoration as observed at Earth gravity.”
Journal Have an effect on Situation: 3.5
Funding: “This work was supported by NASA award No: 80NSSC18K1664 and NASA Kentucky beneath NASA award No: NNX15AR69H.”
3
Poplaski V, Sawyer FM, Blutt SE.
The small intestinal microbiome: Vibing with intestinal stem cells.
Microbiota and Host. 2023 Oct 1. On-line ahead of print.
https://doi.org/10.1530/MAH-23-0012
PI: S.E. Blutt
Remember: From the abstract. “This evaluation highlights evaluation that probes interactions between ISCs [intestinal stem cells] and the microbiome inside the small intestine to aspect the current understanding of microbial regulation of ISCs. Outcomes from these analysis current crucial info which may be exploited to find out therapeutic targets or develop novel preventative therapies to take care of intestinal sicknesses.” This textual content may be obtained on-line with out value.
Journal Have an effect on Situation: Not accessible for this journal
Funding: “This work was supported by the Nationwide Institute of Effectively being grants U01- DK103168, and U19- AI116497, and the Translational Evaluation Institute for Home Effectively being grant – NNX16AO69A.”
4
Smith LT, Walsh RFL, Goel N, Alloy LB.
Social jetlag and trajectories of mood indicators and reward responsiveness in individuals at low-risk, high-risk, and with bipolar spectrum issues: An ecological momentary analysis look at.
Psychiatry Evaluation. 2023 Nov;329:115499.
https://doi.org/10.1016/j.psychres.2023.115499
PI: N. Goel
Journal Have an effect on Situation: 11.3
Funding: “Namni Goel was supported partly by Nationwide Aeronautics and Home Administration (NASA) grants NNX14AN49G and 80NSSC20K0243 and Nationwide Institutes of Effectively being grant R01DK117488. …”
5
Coulombe JC, Maridas DE, Chow JL, Bouxsein ML.
Small animal DXA [dual-energy X-ray absorptiometry] instrument comparability and validation.
Bone. 2023 Sep 29;116923. On-line ahead of print.
https://doi.org/10.1016/j.bone.2023.116923
PI: M.L. Bouxsein
Journal Have an effect on Situation: 4.1
Funding: “This look at was funded by NASA Human Evaluation Program grant 80NSSC19K0534. …”
6
Trovao NS, Pan V, Goel C, Gallego-García P, Liu Y, Barbara C, Borg R, Briffa M, Cilia C, Grech L, Vassallo M, Treangen TJ, Posada D, Beheshti A, Borg J, Zahra G.
Evolutionary and spatiotemporal analyses reveal plenty of introductions and cryptic transmission of SARS-CoV-2 VOC/VOI in Malta.
Microbiol Spectr. 2023 Oct 6;e0153923. On-line ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37800925
Remember: This textual content may be obtained on-line with out value.
Journal Have an effect on Situation: 9.0
Funding: A. Beheshti is affiliated with NASA Ames Evaluation Coronary heart.
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Completely different papers of curiosity:
1
Blaber AP, Sadeghian F, Naz Divsalar D, Scarisbrick IA.
Elevated biomarkers of neural harm in older adults following head-down mattress rest: Hyperlinks to cardio-postural deconditioning with spaceflight and getting older.
Entrance Hum Neurosci. 2023 Sep 26;17:1208273.
https://doi.org/10.3389/fnhum.2023.1208273
Remember: Head-down tilt bedrest look at. This textual content is part of Evaluation Matter “Brains in Home: Outcomes of Spaceflight on the Human Thoughts and Habits-Amount II” (https://www.frontiersin.org/research-topics/47491/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview). The Evaluation Matter moreover consists of articles from earlier Current Consciousness Lists #1,041 https://doi.org/10.3389/fphys.2023.1141078; #1,046 https://doi.org/10.3389/fncir.2023.1135434; #1,051 https://doi.org/10.3389/fphys.2023.1146096; # 1,053 https://doi.org/10.3389/fphys.2023.1141015; #1,056 https://doi.org/10.3389/fnins.2023.1180314; #1,059 https://doi.org/10.3389/fncir.2023.1190582 and https://doi.org/10.3389/fncir.2023.1197278; #1,061 https://doi.org/10.3389/fphys.2023.1201253; and #1,062 https://doi.org/10.3389/fncir.2023.1170395. This textual content may be obtained on-line with out value.
2
Smith L.
Home station and spacecraft environmental circumstances and human psychological effectively being: Specific recommendations and suggestions.
Life Sci Home Res. 2023 Oct 11. On-line ahead of print.
https://doi.org/10.1016/j.lssr.2023.10.001
Remember: From the abstract: “This manuscript serves to briefly evaluation what is believed in regards to the precept components of an space habitat (e.g., noise ranges, lighting, air prime quality, privateness, vegetation, and so forth.), and provide specific and clear recommendations for mission planners and home habitat designers. The place relevant, options for future evaluation are highlighted.”
3
White NJ, Wenthe A.
Managing hemostasis in home.
Arterioscler Thromb Vasc Biol. 2023 Oct 5. Analysis. On-line ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37795614
Remember: From the abstract: “Human home journey requires publicity to weightlessness, ionizing radiation, isolation, and austerity. A contemporary report of inside jugular vein thrombosis in astronauts in low Earth orbit confirms that these exposures moreover affect vascular biology to have an effect on sicknesses of thrombosis and hemostasis. This momentary evaluation summarizes the recognized influences of home journey on irritation, blood coagulation, and the cardiovascular system and conceptualizes how they might combine to affect thrombosis and hemostasis.”
4
Pagliarello R, Bennici E, Di Sarcina I, Villani ME, Desiderio A, Nardi L, Benvenuto E, Cemmi A, Massa S.
Outcomes of gamma radiation on engineered tomato biofortified for home agriculture by morphometry and fluorescence-based indices.
Entrance Plant Sci. 2023 Oct 9;14:1266199.
https://doi.org/10.3389/fpls.2023.1266199
Remember: This textual content is part of Evaluation Matter “Progressing the Manner ahead for Home Agriculture” (https://www.frontiersin.org/research-topics/52433/progressing-the-future-of-space-agriculture#overview). The Evaluation Matter moreover consists of articles from earlier Current Consciousness Lists #1,055 https://doi.org/10.3389/fpls.2023.1194753 and #1,069 https://doi.org/10.3389/fpls.2023.1265458. This textual content may be obtained on-line with out value.
5
Miao LW, Liu TZ, Photo voltaic YH, Cai N, Xuan YY, Wei Z, Cui BB, Jing LL, Ma HP, Xian CJ, Wang JF, Gao YH, Chen KM.
Simulated microgravity-induced oxidative stress and lack of osteogenic potential of osteoblasts could also be prevented by security of main cilia.
J Cell Physiol. 2023 Oct 5. On-line ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37796139
Remember: A random positioning machine was used on this look at.
6
Zhou Y, Lv W, Peng X, Cheng Y, Tu Y, Observe G, Luo Q.
Simulated microgravity attenuates pores and pores and skin wound therapeutic by inhibiting dermal fibroblast migration by means of F-actin/YAP signaling pathway.
J Cell Physiol. 2023 Oct 5. On-line ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37795566
Remember: From the abstract: “Pores and pores and skin and its cell components repeatedly subject to extrinsic and intrinsic mechanical forces and are mechanical delicate. Disturbed mechanical homeostasis may lead to modifications in pores and pores and skin capabilities. Gravity is the integral mechanical strain on the Earth; nonetheless, how gravity contributes to the maintenance of pores and pores and skin carry out and the way in which microgravity in home impacts the wound therapeutic are poorly understood. Proper right here, using microgravity analogs, we current that simulated microgravity (SMG) inhibits the therapeutic of cutaneous wound and the buildup of dermal fibroblasts inside the wound mattress.”
7
Cui X, Observe W, Xue Y, Jing H, Lei M, Ma H, He X, Zou P, Wu B, Wang J.
Numerical analysis of micro lunar mud deposition inside the human nasal airway.
J Hazard Mater. 2024 Jan 5;461:132682.
https://pubmed.ncbi.nlm.nih.gov/37793250
8
Submit TE, Heijn LG, Jordan J, van Gerven JMA.
Sensitivity of cognitive carry out assessments to acute hypoxia in healthful subjects: A scientific literature evaluation.
Entrance Physiol. 2023 Oct 11;14:1244279.
https://doi.org/10.3389/fphys.2023.1244279
Remember: This textual content may be obtained on-line with out value.
9
Kang JH, Lee HY, Kim NY, Lee DS, Yim M.
Extracellular Prdx1 mediates bacterial an an infection and inflammatory bone sicknesses.
Life Sci. 2023 Nov 15;333:122140.
https://pubmed.ncbi.nlm.nih.gov/37797684
10
Cazenave L, Einenkel M, Yurkewich A, Endo S, Hirche S, Burdet E.
Hybrid robotic and electrical stimulation assist can enhance effectivity and reduce psychological demand.
IEEE Trans Neural Syst Rehabil Eng. 2023 Oct 10. On-line ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37815973
Remember: This textual content may be obtained on-line with out value.
11
Luyken MC, Appenzeller P, Scheiwiller PM, Lichtblau M, Mademilov M, Muratbekova A, Sheraliev U, Abdraeva A, Marazhapov N, Sooronbaev TM, Ulrich S, Bloch KE, Furian M.
Time course of cerebral oxygenation and cerebrovascular reactivity in Kyrgyz highlanders. A five-year potential cohort look at.
Entrance Physiol. 2023 Oct 10;14.
https://doi.org/10.3389/fphys.2023.1160050
Remember: This textual content is part of Evaluation Matter “Neurological Dysfunction and Diseases in Extreme Altitude” (https://www.frontiersin.org/research-topics/48777/neurological-dysfunction-and-diseases-in-high-altitude#overview). The Evaluation Matter moreover consists of articles from earlier Current Consciousness Lists #1,037 https://doi.org/10.3389/fphys.2023.1133059 and #1,065 https://doi.org/10.3389/fphys.2023.1191058. This textual content may be obtained on-line with out value.
12
Modi AD, Parekh A, Patel ZH.
Methods for evaluating gait associated dynamic steadiness and coordination in rodents.
Behav Thoughts Res. 2024 Jan 5;456:114695. Analysis.
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